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AHRQ DEcIDE-2 Network

Solicitation Number: AHRQ1010006
Agency: Department of Health and Human Services
Office: Agency for Healthcare Research and Quality
Location: Contracts Management
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Added: Feb 18, 2010 5:09 pm
The Agency for Healthcare Research and Quality (AHRQ) of the U.S. Department of Health and Human Services (DHHS) is seeking potential sources qualified under North American Industry Classification (NAICS) Code 541690 ($7.0 million). These firms must have the capability to conduct original research, develop new scientific methods, carry out interventional studies, incorporate professional and consumer input into research plans, develop multi-center research protocols, analyze existing health care data, and implement collaborative studies employing prospective designs with other designated institutions. This research initiative is titled the “Developing Evidence to Inform Decisions about Effectiveness Network (DEcIDE-2)” and assists AHRQ and other Federal Agencies with patient-centered outcomes research, including studies on comparative clinical effectiveness as authorized by Section 1013 of the Medicare Modernization Act of 2003 (MMA) and subsequent legislation such as the American Recovery and Reinvestment Act (ARRA) of 2009. The overarching goal of comparative effectiveness research is to improve patient health outcomes by providing objective scientific evidence to inform the health care decisions of patients, their caregivers, clinicians, and policy makers.

The primary objective of the DEcIDE-2 Network will be to conduct multiple research studies in close collaboration with AHRQ staff and other institutions that comprise AHRQ’s Effective Health Care program. The main focus of these research studies will be to examine the comparative clinical effectiveness and safety of health care interventions including the manner in which diseases, disorders, and other health conditions can effectively and appropriately be prevented, diagnosed, treated, monitored, and managed. the following are requirements of this project:

1) conduct of prospective observational or interventional studies that evaluate strategies for improving the effectiveness and efficiency of the Medicare, Medicaid, SCHIP and other health insurance programs, including ways in which medical therapies and diagnostic tests are provided, organized, managed, and delivered;

2) development of valid scientific methods, measures, and instruments that can be rapidly applied to facilitate comparative effectiveness research, clinical care, or program evaluation;

3) establishment, maintenance, operation, and analysis of clinical registries that enroll participants based on characteristics such as demographics, disease status, drug exposure, or use of medical device(s);

4) evaluation of distributed research networks, data standards, controlled terminologies, and ontologies that enable information system interoperability, comparative effectiveness research, safety studies, registry development and knowledge sharing while maintaining privacy;

5) conduct of retrospective and prospective studies to assess various factors that may affect therapeutic effectiveness and patient health outcomes;

6) provision of technical assistance or consultative support to AHRQ on methods for conducting health outcomes research on the comparative effectiveness and safety of medications, diagnostics, surgery, health systems, and other healthcare interventions;

7) provision of technical assistance in establishing, maintaining, and mining clinical repositories and databases for comparative effectiveness and safety research;

8) evaluation of the feasibility of using administrative, claims, or other existing health data to a) improve oversight, b) support quality, safety, effectiveness, and efficiency initiatives, c) and estimate the impact on patients and populations of changes in clinical practices and insurance program policies;

9) conduct accelerated research that examines the a) outcomes, b) comparative clinical effectiveness, c) safety, and d) appropriateness of prescription medications and other therapies, using existing electronic health databases; and

10) implementation of selected economic analysis including value of information or other quantitative methods for prioritizing the initiation of new research studies.

A series of multiple IDIQ contracts will be awarded for a period of three years. The task orders may be funded with American Recovery and Reinvestment (ARRA) funds, which would require specific reporting requirements. Award is expected on or about July 9, 2010 with proposals due approximately six weeks thereafter. In addition to the solicitation being available on this site, it will also be available for downloading from the internet on AHRQ’s website at It is the offeror’s responsibility to monitor the FBO site for release of the solicitation, download their own copy of the solicitation, and monitor the site for any subsequent amendments. Since it is not known who is downloading the solicitation, a bidders list will not be available.

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Amendment 1

Posted Date:
February 22, 2010
Description: Amendment to Presolicitation Notice DEcIDE-2
540 Gaither Road
Rockville, Maryland 20850
Mary B Haines
Phone: 301 427-1786