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NONHUMAN PRIMATE CORE FUNCTIONAL GENOMICS LABORATORY FOR AIDS VACCINE RESEARCH AND DEVELOPMENT

Solicitation Number: RFP-NIAID-DAIDS-NIHAI2012142
Agency: Department of Health and Human Services
Office: National Institutes of Health
Location: National Institute of Allergy and Infectious Diseases
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There have been modifications to this notice. To view the most recent modification/amendment, click here
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RFP-NIAID-DAIDS-NIHAI2012142
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Award
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Added: Apr 26, 2012 2:49 pm Modified: Jun 08, 2012 1:53 pmTrack Changes
The purpose of this modification is to revise the "Description" field of the Pre-Solicitation announcement to incorporate a brief description of the Electronic Contract Proposal Submission (eCPS) website requirements that are applicable to this solicitation:

The NIAID provides immunological and virological support for nonhuman primate (NHP) conducted at NIAID's Simian Vaccine Evaluation Unit (SVEU) contract sites and by DIADS-supported vaccine researchers through three existing NHP Core Laboratories (NHP Core Labs): the Humoral Immunology Core Lab, the Cellular Immunology Core Lab, and the Viral Ribonucleic Acid (RNA) Core Lab. The Functional Genomics NHP Core Laboratory will thus become a fourth NHP Core Lab. The objective of the Core Laboratories has been to insure standardization and comparability of functional genomics services and assays conducted for these SVEU and DAIDS-supported preclinical NHP studies.

The purpose of the proposed contract will be to provide support for a Functional Genomics NHP Core Laboratory for the conduct and improvement of assays designed to generate specific quantitative genomic expression profiles and network diagrams from RNA samples obtained from NHPs enrolled in priority SVEU protocols and DAIDS-supported investigator-initiated NHP studies.


The Contractor shall compile and analyze the generated data using bioinformatics and biocomputing tools (e.g., unbiased hierarchical clustering methods, sophisticated network algorithms, etc.) with the intent of identifying gene signatures that could potentially define correlates of protection and predict vaccine efficacy.


It is anticipated that one cost reimbursement, term type contract will be awarded for a 1-year Base period plus four 1-year options for a possible total period of performance of 5 years beginning on or about June 17, 2013. The performance requirement will be for the delivery of 3.85 full time equivalents (FTEs) per year for the base period (Year 1) and option periods (Years 2 through 5), which may be unilaterally exercised by the Government. In addition, the Government may unilaterally exercise options to accommodate significant increases in work to be provided for the base period and option periods. Should the Government elect to exercise these options, the Contractor shall provide resources for the unanticipated increase in work volume by .95 FTE for each option exercised. The Government may exercise an option up to two times in any year of the contract.

For this solicitation, the NIAID requires proposals to be submitted in three methods: (1) Paper, (2) Disc (CD or DVD), and (3) Online via the NIAID Electronic Contract Proposal Submission (eCPS) website. The content of the paper, disc, and online proposals must be identical. Submission of proposals by facsimile or e-mail is not acceptable.


For directions on using eCPS, go to the website https://ecps.niaid.nih.gov and then click on "How to Submit."


To submit online using eCPS, offerors must have a valid NIH electronic Research Administration (eRA) Commons account, which provides authentication and serves as a vehicle for secure transmission of documents and communication with the NIAID. The eRA Commons registration process may take up to 4 weeks. For more information, please see http://era.nih.gov/applicants/how-to_steps.cfm#register


Any responsible offeror may submit a proposal which will be considered by the Agency. This RFP will be available electronically on/about May 14, 2012, and may be accessed through FedBizOpps http://www.fedbizopps.gov/. This notice does not commit the Government to award a contract. No collect calls will be accepted. No facsimile transmissions will be accepted.

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Solicitation 1

Type:
Solicitation
Posted Date:
May 14, 2012
Description: Solicitation Package

Amendment 1

Type:
Mod/Amendment
Posted Date:
July 20, 2012
Description: The purpose of Amendment 1 is to:

1. Provide responses to questions from potential offerors regarding the solicitation.

2. Revise ATTACHMENT 5, ADDITIONAL BUSINESS PROPOSAL INSTRUCTIONS, to revise SECTION 3, paragraph 1., and SECTION 5, paragraph B.

Amendment 2

Type:
Mod/Amendment
Posted Date:
September 7, 2012
Description: The purpose of Amendment 2 is to:

1. Provide responses to questions from potential offerors regarding the solicitation.

2. Revise ARTICLE H.9. INFORMATION AND PHYSICAL ACCESS SECURITY, to revise the Position Sensitivity Levels and the Security Categories and Levels.

3. Revise SECTION L INSTRUCTIONS, CONDITIONS, AND NOTICES TO OFFERORS, paragraph 2, Instructions to Offerors, paragraph b, Technical Proposal Instructions, subparagraph 5, Information and Physical Access Security, is hereby revised to amend the Position Sensitivity Levels and the Security Categories and Levels.
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Office of Acquisitions
6700 B Rockledge Room 3214 MSC7612
Bethesda, Maryland 20892-7612
:
Robert J. Corno,
Contract Specialist
Phone: 3014513691
Fax: 3014804675
:
John Manouelian,
Contracting Officer
Phone: 301-496-0612
Fax: 301-402-0972