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Folded Non-Natural Polymers with Biological Function (Fold F(x))

Solicitation Number: DARPA-BAA-14-13
Agency: Other Defense Agencies
Office: Defense Advanced Research Projects Agency
Location: Contracts Management Office
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DARPA-BAA-14-13
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Presolicitation
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Added: Jan 07, 2014 9:25 am
The DARPA Fold F(x) program objective is to develop processes enabling the rapid synthesis, screening, sequencing and scale-up of folded, non-natural, sequence-defined polymers with expanded functionality. The program will specifically address the development of non-natural affinity reagents that can bind and respond to a selected target, as well as catalytic systems that can either synthesize or degrade a desired target. DARPA anticipates that successful efforts will include (1) novel synthetic approaches that yield large libraries (>109 members) of non-natural sequence-defined polymers; (2) flexible screening strategies that enable the selection of high affinity/specificity binders and high activity/selectivity catalysts from the non-natural libraries; (3) demonstration that the screening approach can rapidly (<4 days) yield affinity reagents or catalysts against targets of interest to the DoD; and (4) demonstration of scalability and transferability to the DoD scientific community.

See attached DARPA-BAA-14-13.
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DARPA-BAA-14-13

Type:
Other (Draft RFPs/RFIs, Responses to Questions, etc..)
Label:
DARPA-BAA-14-13
Posted Date:
January 7, 2014
Description: DARPA-BAA-14-13
Description: DARPA-BAA-14-13 Executive Summary
:
675 North Randolph Street
Arlington, Virginia 22203-2114
United States
:
D. Tyler McQuade,
Dr.